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AKINTUNDE, Jacob Kehinde 


Short Profile

Doctor Jacob K. Akintunde is a Reader of Molecular Toxicology and Medical Biochemistry at the
Department of Biochemistry; College of Biosciences, Federal University of Agriculture, Abeokuta
(FUNAAB), Nigeria. He obtained his MSc in Biochemistry (Molecular Drug Metabolism and Toxicology)
from the University of Ibadan, Nigeria. He later received his Postgraduate Diploma in Food Agricultural and
Biological Engineering from African Renaissance Institute of Science and Technology (ARIST), Abuja,
Nigeria. Thereafter, he bagged his PhD degree in Applied Biochemistry from Federal University of
Technology, Akure, Nigeria. Before moving to FUNAAB in 2017, Dr. Jacob was Lecturer II and Lecturer I
at the Faculty of Basic Medical Sciences, Kwara State University, Nigeria and Faculty of Public Health,
College of Medicine, University of Ibadan, Nigeria, respectively.
Doctor Jacob has broad background in areas of Molecular Drug Metabolism, Food Therapy and Toxicology
which includes (a) elucidating biochemical/molecular mechanisms of Huntington/ Alzheimer’s/Parkinson’s
disease and metabolic diseases particularly hypertension. (b) Understanding the role of oxidative stress in
hippocampus, hypothalamus, basal ganglia, striatum and cerebral cortex disorders, (c) examining
pathogenesis of environmental compounds in cardiovascular organs, (d) developing new chemotherapeutic
agents and functional food therapies for prevention/inhibition of common metabolic diseases, and (e)
therapeutic use of natural products to treat breast/prostate cancer, cardiopulmonary disorders and genetic
diseases caused by anthropogenic/environmental and epigenetic toxicants.
Doctor Jacob’s works had been supported by grants from Nigeria TETFUND schemes. He has mentored
above 61 undergraduate students, 19 masters’ students and 4 doctoral students. He has received several
honours and awards including undergraduate Scholarship Awards, pioneer staff adviser to National
Association of Biochemistry Students (NABS) KWASU chapter. Doctor Jacob was rated among top 500
Nigerian scientists (2020) by Scopus. Additionally, he is a member of Society of Toxicology (SOT),
National Society of Functional foods and Nutraceuticals among others. Lastly, he has publications in
national and International peer-reviewed Journals.

 Ph.D. Applied Biochemistry. 2014
 PGD. Food Agriculture and Biological Engineering. 2012
 M.Sc. Biochemistry (Molecular Drug Toxicology) 2008
 B.Sc. Environmental Management & Toxicology. 2003

 Efficacy of medicinal flavonoid from Bitter Gourd on cognitive disorders in a sub-chronic
prostrate induced pathology using hypertensive animal model
 Corrective therapy of naringin against renal failure related to Lesch-Nyhan Disease in a
rat model via NOS-cAMP-PKA and BDNF/TrkB pathways
 Mantisa religiosa egg-cake prevents ocular vasoconstriction syndrome triggered by
inflammatory mediators via NOS/cGMP/PKG signalling pathway in rats exposed to
mixture of flavouring enhancers
 Application of Garcinia kola oil constituents against GABA A ergic system alteration in
Huntington’s disease using animal model
 Exposure to chemical hazards, long work duration and its associated symptoms of
neurological disorders among workers of plastic industries in Anambra State
 Impact assessment of workplace exposure on prostate of workers in crude oil industries
of Delta State, Nigeria
 Effect of occupational health risks on pulmonary health sweepers in Ikorodu Local
Government Area, Lagos State


 Development of selenium nanoparticles from Corchorus olitorius L. leaves to treat
hypertension and polycystic ovarian syndrome in rats
 Effect of lycopene on oculo-pulmonary nucleotides, immune T-cells and molecular
responses in PM 2.5 wood smoke induced chronic obstructive pulmonary disease in rats.
 Effect of thymoquinone on hypertensive maternal parents and developmental neuropathy
of F1 male generation in rats exposed to mixture of Bisphenol-A analogues
 Biochemical and molecular responses of Garcinia kola oil on breast cancer and
hypertension using in-silico and in vivo approaches

Rated among top 500 Nigerian scientists by Scopus (20th April, 2020)
 Pioneer Staff Adviser Awards by National Association of Biochemistry Students (NABS)
KWASU chapter (2014)
 Undergraduate Scholarship Awards by Federal Government (May, 2001)

Head of Department

 Society of Toxicology (SOT)-USA
 International Society of Neurochemistry (ISN)-USA
 Nigeria Society of Biomedical Research.
 Nigerian Society for Experimental Biology (NISEB)
 Nigerian Society of Biochemistry and Molecular Biology (NSBMB).
 National Society of Functional foods and Nutraceuticals (Pharma foods)

 Pharma-Food Congress on the Role of Functional Foods and Nutraceuticals in the Era of
COVID-19 held at Landmark University Omu-Aran, Nigeria, 4-7, October, 2022. Paper
Read: Roasted cashew nut supplement inhibits MCP-1 and inflammatory mediators to
correct hypertension related liver failure induced by mixed-fractionated petroleum
products via NOS-cAMP-PKA signalling pathway in male rats
 Sustaining Biosciences for human and Agricultural Development. 2nd Biennial
Conference held at Postgraduate hall of Federal University of Agriculture, Abeokuta,
Nigeria, 12-15 November, 2019.
 Pharma-Food Congress on Phytomedicine and Functional Foods: Keys to sustainable
Health Care Delivery in Sub-Sahara Africa held at T.I Francis Auditorium of Federal
University of Technology Akure, Nigeria, 21-24, July, 2019. Paper Read: Naringin
protects against Bisphenol-A induced ocular toxicity as implication of catarrh in
hypertensive rat model
 Alexander von Humboldt Kolleg International Conference on Functional Foods and
Nutraceuticals: Translating the knowledge of food bioactive compounds to Effective
Health Care Delivery in Developing World held at Federal University of Technology,
Akure, Nigeria, 2 – 6, April, 2017. Paper Read: Effect of dietary supplementation of
black seed on testicular serum hormones and sperm functions in rats’ exposed to leachate
from battery recycling site.
 Alexander von Humboldt Kolleg International Conference on translating research
findings into policy in developing countries held at the College of Health Sciences,
LAUTECH Osogbo, Nigeria, 24 – 27, January, 2017. Paper Read: Differential
protection of Launea taraxacifolia on cardiac oxidative damage, econucleotidase and
carbohydrate catabolizing enzymes in rats exposed to metropolitan polluted river water
 Alexander von Humboldt Kolleg International Conference on Multidisciplinary Forum on
Molecular Technology: Laying the Foundation for Revolutionized Research in Nigeria


held at Multimedia Centre of Excellence Auditorium, University of Lagos, Lagos, Nigeria.
10- 15th October, 2016. Paper Red: Therapeutic approaches of black seed oil and its
underlying mechanisms against kidney dysfunction in haloperidol-induced male rats.
 5th Biannual Unibadan Conference of Biotechnology for Health and Sustainable
Development, held at UI hotel, Conference centre, University of Ibadan, Ibadan, Nigeria.12-
15th July, 2016. Paper read: (i) Differential protection of black-seed oil on
econucleotidase, cholinesterases and aminergic catabolizing enzyme in haloperidol-
induced neuronal damage of male rats
 Alexander von Humboldt Kolleg international workshop on ethical issues in Research
and Scholarship in Nigeria Universities held at UI hotel, Conference centre, University of
Ibadan, Ibadan, Nigeria.10- 14th February, 2016.
 2nd Annual conference of Environmental Health Sciences held at CESDEV Hall,
Awolowo Avenue, University of Ibadan, Ibadan, Nigeria.1st -5 November, 2015. Paper
read: Effect of Launea taraxacifolia methanolic extract on relevant markers of
spermatogenesis in rats exposed to Surulere polluted river water of Kwara State, Nigeria.
 33rd Annual conference of the Nigerian society of Biochemistry and molecular Biology
(NSBMB), held at University Auditorium, University of Ilorin, Ilorin, Nigeria.11th-14th
November, 2014. Paper read: GC-MS Characterization of methanol extract stem bark of
kigelia africana and its inhibitory property on some key markers linked with infertility in
 4th Biannual Unibadan Conference of Biotechnology for Health and Sustainable
Development, held at Trenchard Hall, University of Ibadan, Ibadan, Nigeria. 1- 4th July,
2014. Paper read: Sub-acute exposure to Mercury induces key markers linked with
neurotoxicity and low level ATP in Rat: Modulatory potentials of Pteleiosis suberosa (stem

Akintunde, J.K: Opeolu B.O and Aina O.O (2010). Exposure to potassium carbonate
emulsion induced Nephro-toxicity in experimental animals. Institution Journal of
Biological Sciences. (3):29-32.
2 Siemuri E.O; Akintunde J.K and Adeyinka E.A (2011). Acid-hydrolysed local
cowpea (Vigna unguiculata) as culture media for laboratory Yeast (Saccaromyces
cerevisiae): International Journal of Research Microbiology. 2(6): 187-191.
3 Adedayo M R; Ajiboye A.E; Akintunde J.K; Odaibo A.D (2011); Single Cell
Protein as Nutritional Enhancers: Journal of Advances in Applied Science Research
2(5): 396-400
4 Ajiboye A.E; Kolawole O.M; Oladosu T.O; Adedayo M.R and Akintunde J.K
(2011). Studies on the microorganisms associated with dried meat (Tinko) sold in
Ilorin. African Journal of Microbiology 5(24):4150-4154.
5 Farombi, EO; Akintunde, JK; Nzute,N; Adedara, IA and Arojojoye O (2011)
Municipal landfill leachate induces hepatotoxicity and oxidative stress in rats. Journal
of Toxicology and Industrial Health. 28(6) 532–541. Published by Sage Publications
Ltd. Available online at
6 Irondi AE, Oboh G and Akintunde JK (2012) Comparative and synergistic antioxidant
properties of Carica papaya and Azadarichta indica leaves. International Journal of
pharmaceutical sciences and research 3(12): 4773-4779.
7 Akintunde J. K, Siemuri E. O, Bello I. J, Dairo K. P , Adedayo M. R, Ajiboye E. A
(2012). Tears Production: Implication for Health Enhancement. Scientific Reports
1(10):476. Available online at doi:10.4172/scientificreports.476
8 Akintunde JK, Ajiboye JA, Siemuri EO, Oyelowo SB, Sunday OJ (2012) SubChronic Treatment of Sildernafil Citrate (Viagra) on some Enzymatic and NonEnzymatic Antioxidants in Testes and Brain of Male Rats. Journal of Pharmacology
and Drug Delivery Resources 1:1
9 Siemuri E.O; Akintunde J.K; Bello I.J and Dairo K.P (2012). Assessment of cytotoxic
effects of methanol extracts of Calliandra portoricensis using Brine Shrimp (Artemia
salina) Lethality Bioassay. Global Journal of Bioscience and Biotechnology. 1 (2):
10 Dairo K.P Akintunde J.K (2012).Evaluation of plant Growth-promoting Rhizobacteria
for the control of bacterial wilt disease of tomato. Global Journal of Bioscience and
Biotechnology.1(2): 253-256.
11 Akintunde J. K; Siemuri E. O; Bello I. J; Dairo K. P; Adedayo M. R and Ajiboye E.
A (2012). Tear production: Implication for Health Enhancement. Scientific Reports.1
(10): 01-08
12 Ajiboye J.A, Akintunde J.K, Oyagbemi A.A, Akinyinka E.O, Arojojoye O
(2012).Influence of Isoniazid Treatment on Microsomal Lipid peroxidation and
Antioxidant Defense Systems of Rats. Journal of Drug Metabolism and Toxicology
3:120. Published by omics. Available online at doi: 10.4172/2157-7609.1000120
13 Ajiboye J.A; Oyagbemi A.A; Akintunde J.K; Akinyinka E.O and Arojojoye O
(2012). Microsomal Lipid Peroxidation, Antioxidant Enzyme Activities in Brain of
Male Rats during Long-Term Exposure to Isoniazid. Journal of Drug Metabolism and
Toxicology 3 (4):100127
14 Akintunde JK, Oboh G (2012) In Vitro Oxidative Damage Induced in Livers, Hearts
and Kidneys of Rats Treated with Leachate from Battery Recycling Site: Evidence for
Environmental Contamination and Tissue Damage. Journal of Clinical and
Experimental Pathology 2:129
15 Irondi A.E; Anokam K.K; Chukwuma P.C; Akintunde J.K and Nurain I.O (2013)
Variation in nutrients composition of Tetrapleura tetraptera fruit at two maturity stages.
International Journal of Biosciences 3 (9): 102-110.
16 Hassan B.O; Siemuri O.E, and Akintunde J.K (2013) Assessment of cytotoxicity,
antioxidant and free radical scavenging activities of the ethylacetate extract of
calliandra portoricensis root bark. International Journal of Pharmaceutical Sciences
and Research 4(5): 1800-1807.
17 Akintunde JK, Ajiboye JA, Siemuri EO, Oyelowo SB, Sunday OJ; Abam E.O; Irondi
A.E (2013) Effect of anti-erectile dysfunction drug on key tissues in healthy male rats.
American Journal of Drug Discovery and Development. 3(2):32-46
18 Akintunde JK, Oboh G (2013) Municipal Auto-Battery Recycling-Site Leachate
Activates Key Enzymes Linked to Non-Insulin Dependent Diabetes Mellitus (NIDDM)
and Hypertension. Journal of Diabetes and Metabolism 4: 235
19 Akintunde, J.K.& Oboh, G. (2013): Exposure to leachate from municipal battery
recycling site: implication as key inhibitor of steroidogenic enzymes and risk factor of
prostate damage in rats. Review of environmental health. 28(2-3):107-15. Published
by De gruyter. Available online at
20 Akintunde, J.K., Oboh, G.& Akindahunsi, A.A. (2013): Testicular membrane lipid
damage by complex mixture of leachate from municipal battery recycling site as
indication of idiopathic male infertility in rat. Journal of interdisciplinary Toxicology.
6(4): 192–197. Published by Versita. Available online at
21 Ajiboye J.A, Akintunde J.K, Oladejo O.S, Sabiu S.A (2015) Chemoprevention of
Silymarin and Vitamin C on Isoniazid Induced Hepatotoxicity in Experimental Rat Model.
Journal of Toxin published. 2 (1):01-03 (USA)
22 Akintunde, J.K.& Oboh, G. (2015): Sub-chronic exposure to leachate activates key
markers linked with neurological disorder in Wistar male rat. Environmental Science
and Pollution Research. 22:18541–18553. Published by springer. Available online at
23 Akintunde, J.K. & Oboh, G. (2015): Depletion of cellular adenosine triphosphate and
hepatocellular damage in rat after sub-chronic exposure to leachate from anthropogenic
recycling site. Human and Experimental Toxicology. 34 (11): 1083-1095. Published
by Sage Publications Ltd. Available online at
24 Akintunde, J.K., Oboh, G.& Akindahunsi, A.A. (2015): Inhibition of key markers
linked with spermatogenesis and cellular ATP by sub-chronic exposure to leachate in a
rat model. Archive Environmental Contamination and Toxicology. 68(1): 159–168.
Published by springer. Available online at
25 Siemuri, E.O., Akintunde, J.K.& Salemcity, A.J. (2015): Effects of sub-acute
methanol extract treatment of Calliandra portoricensis root bark on antioxidant defence
capacity in an experimental rat model. Journal of Basic Clinical Physiology and
Pharmacology. 26(4):375-382. Published by de gruyter. Available online at
26 Akintunde, J.K.& Bolarin, O.E. (2015): Research on garlic capsule and Seleniumvitamin A, vitamin B, vitamin C applied in therapy of acute hepatocellular damage in a
rat model. Journal of Acute Disease.4(4):298-404.Published by Elsevier. Available
online at
27 Akintunde, J.K., Oboh, G.& Akindahunsi, A.A. (2015). Sub-chronic exposure to
EOMABRS leachate induces germinal epithelial cell lesions, sperm abnormality and
oxidative damage in rats. Asian Pacific Journal of Reproduction. 4 (4): 288–297.
Published by Elsevier. Available online at
28 Nurain I.O; Akintunde J. K; Adebisi K.E; Azeez L.A; Bamisaye F. A; Ajani E. O;
Bewaji C.O (2015). Intake of Powdered Tea Supplemented with Moringa oleifera Leaf
Attenuates Some Haematological Parameters in Malnourished Children. Journal of
Biological and Chemical Research 32 (2): 892-901.
29 Irondi A.E; Iweala E.J; Agboola O.S; Akintunde J.K; Ajiboye J.A (2015) Distribution
of Metabolites and Antioxidant Activity in the Berry and Shoot of Solanum
pseudocapsicum Grown in Nigeria. International Journal of Biochemistry Research &
Review 8(1): 1-9.
30 Akintunde, J.K., Bolarin, E.O.& Akintunde, D.G. (2016): Garlic capsule and
selenium-vitamins ACE combination therapy modulate key antioxidant proteins and
cellular adenosine triphosphate in lisinopril-induced lung damage in rats. Drug
Metabolism and Personalized Therapy. 31(1): 47–54. Published by De gruyter.
Available online at
31 Akintunde JK, Akintunde DG, Irondi EA, Babaita K, Labaika R, Sunday O (2016).
Antioxidants from stem bark of Kigelia africana inhibit free radicals and membrane
lipid damage in rat testes in vitro. Oxidant antioxidant in Medical Science published
by Gesdav, 5(2): 63-69.
32 Akintunde JK, Ajiboye JA, Soyinka OO, Adeyemi AA (2016). Stem Bark Extract
from Alstonia boonei attenuates Cholesterol, Triglyceride and Oxidative Damage via
Low Immunohistochemical Expression in Small Intestinal Tract of Male Rats published
by Journal of Diabetes Metabolism 7: 715.
33 Arojojoye OA, Nwaechefu OO, Ajiboye JA, Akintunde JK (2016). Induction of
oxidative stress in Clarias gariepinus from Eleyele River in Nigeria. Advances in
Environmental Research published by Aensi, 5(3): 179-187 (UK)
34 Akintunde, J.K.& Irechukwu, C.A. (2016): Differential protection of black-seed oil on
econucleotidase, cholinesterases and aminergic catabolizing enzyme in haloperidolinduced neuronal damage of male rats. Therapeutic Advances in Drug Safety.7(4):132-
146. Published by Sage publications Ltd. Available online at
35 Olalubi, A.O., Owoyele, B.V., Ayinla, M.T. & Akintunde, J.K. (2016): Glucose
absorption in the intestine of albino rats. Journal Basic Clinical Physiology
Pharmacology. 27 (4):357-361. Published by De gruyter. Available online at
36 Ilesanmi, A.O., Ekwe, G.J., Ilesanmi, R.I., Ogundele, D.T., Akintunde, J.K.& Olalubi
O.A. (2016): Prevalence of latent eosinophilia among occupational gardeners at
Babcock University, Nigeria. Asian Pacific Journal of Tropical Biomedicine.
6(6):511-515. Published by Elsevier. Available online at
37 Akintunde, J.K. (2017): Functional oil from black seed differentially inhibits aldosereductase and ectonucleotidase activities by up-regulating cellular energy in
haloperidol-induced hepatic toxicity in rat liver. Journal of oleo science. 66 (9): 1051-
1060. Published by Japan Oil Chemists Society. Available online at
38 Ajani, E.O., Sabiu, S., Zakari, M., Olanipekun, B.E., Akintunde, J. K. & Bamisaye,
F.A. (2017): Antioxidant Capacity of Fractionated Extract and Structural Elucidation
of Isolated Compounds from Leaf Extract of Hydrocotyl bonariensis Comm. Exlam,
Journal of Biologically Active Products from Nature.7(3):166-177. Published by
Taylor and Francis. Available online at
39 Akintunde J.K, Labaika R.G (2017). Neuro-Preventive Effect and Elevation of
Cellular Adenosine Triphosphate by PUFAs from Pteleiosis suberosa Stem Bark on
Mercury Sub-Acute Exposed Rats. Journal of acute medicine, 7(1):1-9.
40 Ajiboye J.A, Akintunde J.K, Okewuyi S.O, Okafor U.E (2017). PUFAs from Stem
Bark of Alstonia boonei synergistically modulate diabetic, hepatic and androgenic
damage by low expression of COX-2 and iNOS in rats. Journal of molecular
biomarker and diagnosis 8: 334.
41 Akintunde, J.K.& Abubakar, O.K. (2017): Novel therapeutic approaches of natural oil
from black seeds and its underlying mechanisms against kidney dysfunctions in
haloperidol-induced male rats. Journal of Drug metabolism and personalized
therapy.32 (2):97-107.Published by De gruyter. Available online at
42 Akintunde, J.K.& Babaita, A.K. (2017): Effect of PUFAs from Pteleopsis suberosa
stem bark on androgenic enzymes, cellular ATP and prostatic acid phosphatase in
mercury chloride – Exposed rat. Middle East Fertility Society Journal 22:211-218.
Published by Elsevier. Available online at
43 Irondi, A.E., Akintunde J.K. Agboola S.O.& Boligon A.A. (2017): Blanching
influences the phenolics composition, antioxidant activity and inhibitory effect of
Adansonia digitata leaves extract on α-amylase, α-glucosidase and aldose reductase.
Journal of Food Science and Nutrition. 5 (2): 233-242. Published by Wiley and Sons
Ltd. Available online at 10.1002/fsn3.386
44 Akintunde, J.K.& Oboh, G. (2017). Nephritic cell damage and antioxidant status in rats
exposed to leachate from battery recycling industry. Journal of Interdisciplinary
Toxicology. 9(1): 1–11. Published by De gruyter. Available online at
45 Akintunde, J.K, Irondi, A.E., Ajani, E.O.& Olayemi, T.V. (2018): Neuroprotective
effect of dietary black seed flour on key enzymes linked with neuronal signalling
molecules in rats exposed to mixture of environmental metals. Journal of Food
Biochemistry 42 (2):1-11. Published by Wiley Black-well. Available online at
46 Akintunde, J.K., Irondi, A.E, Ajani, E.O.& Olayemi, T.V. (2018): Dietary inclusion
of black seed flour inhibits reproductive alterations via signal transduction by depleting
ectoenzyme, adenosine deaminase and acetylcholinesterase activities in rats intoxicated
with mixed environmental metals. Journal of Biologically Active Products from
Nature, 8 (6):376-392. Published by Taylor and Francis. Available online at
47 Adedayo, M. R., Akintunde, J.K., Sani, A.& Boligon, A.A. (2018): Effect of dietary
supplement from mono-culture fermentation of Moringa oleifera seeds by Rhizopus
stolonifer on hematology and markers linked to hypercholesterolemia in rat model.
Food Science and Nutrition.6 (7):1826-1848. Published by John Wiley and Sons Ltd.
Available at 10.1002/fsn3.729.
48 Akintunde, J.K., Aina, M.O. & Boligon, A.A. (2018): Launaea taraxacifolia (Amin
MS ex c. Jelfney) inhibits oxidative damage and econucleotidase followed by increased
cellular ATP in testicular cells of rats exposed to metropolitan polluted river water.
Journal of Basic and Clinical Physiology and Pharmacology, 29 (2):141-
153.Published by De gruyter. Available online at
49 Akintunde J.K, Jimoh Y.O, Boligon A.A (2018). Essential Oil from Nigella Sativa
Seed Differentially Ameliorates Steroid Genesis, Cellular ATP and Prostate Functions
in Anti-Psychotic Drug-Induced Testicular Damage of Rats. Journal of Clinical
Toxicology, 8 (1):01-09.
50 Akintunde, J.K., Obisesan, O.O., Akinsete, S.J.& Adegoke, A.M. (2019): Diet from
Mantisa religiosa-egg case abolishes pulmonary dysfunctions triggered by sub-acute
exposure to aerosolized-petroleum hydrocarbons in rat model. Clinical Nutrition
Experimental. 26:44-58. Published by Elsevier. Available online at
51 Akintunde, J.K.& Woleola M.T. (2019): Impairment of neuro-renal cells on exposure
to cosmopolitan polluted river water followed by differential protection of Launea
taraxacifolia in male rats. Comparative Clinical Pathology. 28:1245-1257. Published
by Springer. Available online at https://doi: org/10.1007/s00580-019-02898-y.
52 Akintunde, J.K., Irondi, A.E., Ajani, E.O.& Olayemi, T.V. (2019): Diet formulated
with black seed flour activates regulatory androgenic enzymes and neuroendocrine
hormones in leachate-exposed reproductive damage of rat testes. Journal of Nutrition
and Intermediary Metabolism. 15: 70–77. Published by Elsevier. Available online at
53 Akintunde, J.K., Farouk, A.A.& Mogbojuri, O. (2019): Metabolic treatment of
syndrome linked with Parkinson’s disease and hypothalamus pituitary gonadal
hormones by turmeric curcumin in Bisphenol-A induced neuro-testicular dysfunction
of wistar rat. Biochemistry and Biophysics Reports. 17: 97–107. Published by Elsevier.
Available online at 10.1016/j.bbrep.2018.12.004
54 Kuyooro, S.E., Akintunde, J.K., Okekearu, F.C.& Maduagwu, E.N. (2019):
Toxicokinetics and biliary excretion of N-nitrosodiethylamine in rat supplemented with
low and high dietary proteins. Journal of dietary supplements. 16(5):506-520.
Published by Taylor and Francis. Available online at
55 Akintunde, J. K., Ayeni, S.A., Adeoye, M.A.& Shittu, A.O. (2020): Rat liver and
kidney post-mitochondrial dysfunction by addition of chronic mixed metal intoxication
and hepatorenal wellness mediated by phenolic components from Croton zambiscus
leaves. Environmental Toxicology and Pharmacology 74:103293. Published by
Elsevier. Available online at
56 Akintunde, J.K., Abioye, J.B.& Ebinama, O.N. (2020): Potential protective effects
of naringin on oculo-pulmonary injury induced by wood smoke PM10 exposure by
modulation of oxidative damage and acetylcholine esterase activity in a rat model.
Current Therapeutic Research. 92:100586 Published by Elsevier. Available online at
57 Akintunde, J.K., Imhade, I.A.& Oboh G. (2020): Egg case concentrate of Mantis
religiosa abrogates the accumulation of cadmium in muscular and bone tissues of
African catfish via activation of nitric oxide and myeloperoxidase activity. Journal of
food Biochemistry. 44 (6):1-11. Published by Wiley Black-well. Available online at
58 Akintunde, J.K., Akintola, T. E., Aliu, F.H., Fajoye, M. O. & Adimchi, S.O. (2020):
Naringin regulates erectile dysfunction by abolition of apoptosis and inflammation
through NOS/cGMP/PKG signalling pathway on exposure to Bisphenol-A in
hypertensive rat model. Reproductive Toxicology. 95: 123–136. Published by Elsevier.
Available online at
59 Akintunde, J.K., Akintola., T.E., Hammed, M.O., Amoo, C.O., Adegoke, A.M.&
Ajisafe. L.O. (2020): Naringin protects against Bisphenol-A induced oculopathy as
implication of cataract in hypertensive rat model. Biomedicine and Pharmacotherapy.
126: 110043. Published by Elsevier. Available online at
60 Dosumu, O.A., Rotimi, S.O., Akintunde, J.K., Adeleye, O.O., Sani, L.O., Omotosho
O.O., Osinuga, K.T., Taiwo, O.A. & Ojo, O.A. (2020): Effect of vitamin K dietary
supplementation in pulmonary dysfunction induced by 7,12-dimethylbez[a]anthracene
in rat. Journal of Biochemical and Molecular Toxicology 34(12): e22584. Published
by John Wiley and Sons Inc. Available online at
61 Akintunde, J.K., Akintola, T.E., Adenuga, G.O., Odugbemi, Z.A., Adetoye, R.O.&
Akintunde, O.G. (2020): Naringin attenuates Bisphenol-A mediated neurotoxicity in
hypertensive rats by abrogation of cerebral nucleotide depletion, oxidative damage and
neuroinflammation. Neurotoxicology. 81:18–33. Published by Elsevier. Available
online at
62 Akintunde, J.K., Oyedibu, G.O., Olanipekun, N.J.& Olaleye, O.A. (2021): Modulation
of cardiopulmonary toxicity and oxidative stress by phenolic-rich fraction of Croton
zambiscus leaves in rat exposed to chronic mixture of environmental toxicants.
Cardiovascular toxicology. 20 (6):1-16. Published by Springer. Available online at
63 Akintunde, J.K., Farai, T.I., Arogundade, M.R., & Adeleke, J.T. (2021): Biogenic zincoxide nanoparticles of Moringa oleifera leaves abrogates rotenone induced
neuroendocrine toxicity by regulation of oxidative stress and acetylcholinesterase
activity. Biochemistry and Biophysics Reports.26:1-10. Published by Elsevier.
Available online at 10.1016/j.bbrep.2021.100999
64 Akintunde, J.K., Ibrahim, L.B., Omotosho, O.D., & Boligon A.A. (2021): Depletion
of synaptosomal enzymes associated with neurotoxicity and ovarian dysfunction by
phenolic antioxidants of Croton zambsicus leaves in rats exposed to chronic mixture of
anthropogenic toxicant. Metabolism Open. 10:1-14. Published by Elsevier. Available
online at 10.1016/j.metop.2021.100097
65 Akintunde J.K, Ajiboye J. A, Siemuri E.O & Olabisi O. O. (2021): Fansidar drug
induces cytotoxicity in some vital tissues in a rat model: combination defensive
effect of selenium and zinc capsules. Therapeutic Advances in Drug Safety.
Published by Sage Publications Ltd. Available online
66 Akintunde J.K, Omoniyi O.R, Folorunsho O.E, Moses C.A (2021). Meta-inhibition of
ocular and gastrointestinal dysfunctions by phenolic-rich fraction of Croton zambiscus
leaves in a rat model exposed to chronic mixed metals. Cutaneous and Ocular
Toxicology. Published by Taylor and Francis. Available online
67 Okareh O.T, Adetoba M.M, Akintunde J.K, Alarape S.A (2021). Effects of different
Cooking Processes on Bioavailability of Mercury and Arsenic in Exposed African
Catfish (Clarias gariepinus, Burchell, 1822) Bionature 41 (1): 39-49.Published by
Global Press Hub. Available online at
68 Akintunde J.K & Abiola A. E. (2022): Active elements from Launea taraxacifolia
upgrades cardiovascular integrity by attenuation of ectonucleotidase and
carbohydrate-hydrolysing enzymes in rat exposed to metropolitan polluted-
river water. Phytomedicine plus 2: 100245. Published by Elsevier. Available
online at
69 Akintunde J.K, Abinu O.S, Taiwo K.F, Sodiq R.A, Folayan A.D, Ate A.D (2022).
Disorders of Hippocampus Facilitated by Hypertension in Purine Metabolism
Deficiency is Repressed by Naringin, a Bi‑flavonoid in a Rat Model via
NOS/cAMP/PKA and DARPP‑32, BDNF/TrkB Pathways. Neurotoxicity research 40
(4):1-19. Published by Springer. Available online at
70 Adeleye O.O, Dosumu O.A, Akintunde J.K, Ugwor E.I, Abatan M.O, James A.S,
Oyeniran A.O, Ajetunmobi A.A, Ilori O.T, Eromosele C.O (2022). Behavioural
Patterns and Growth Performance of Male Wistar Rats Exposed to Cigarette Smoke:
Effects of Curcumin and Hesperidin. Folia Veterinaria 66 (3): 19-27. Published by
Sciendo. Available online at 10.2478/fv-2022-002
71 Akintunde J.K, Akomolafe V.O, Taiwo O.A, Ahmad I, Patel H, Osifeso A, Adefuye
O.O, Ojo O.A (2022). Antihypertensive activity of Roasted cashew nut in mixed
petroleum fractions-induced hypertension: An in vivo and in silico approaches.
Heliyon. 8 (12):e12339.Published by Elsevier. Available online at
72 Akintunde J.K, Lateef S.A, Amadi C.J, Okoh O.S. (2023). Ethylene glycol and plantain
peel ripened with calcium carbide inhibit reproductive mediators in male rats.
Endocrine and Metabolic Disorder. 11:100130.Published by Elsevier. Available
online at http://dx.
73 Akintunde J.K, Olayinka M.C, Ugbaja V.C, Akinfenwa C.A, Akintola A.J, Akamo A.J,
Bello I.J. (2023). Downregulation of inflammatory erectile dysfunction by Mantisa
religiosa egg-cake through NO-cGMP-PKG dependent NF-kB signaling cascade
activated by mixture of salt intake. Toxicology Reports 10:633-646. Published by
Elsevier. Available online at
74 Adedayo, M.R., Akintunde, J.K, Sani, A. & Boligon, A.A. (2023): Effect of nutriment
from monoculture fermentation of Adasonia digitata seeds by Penicilium chrysogenum
on haematology and functional endpoints of intra and extrahepatic tissues in rats.
Medicine in microecology .17:100085. Published by Elsevier. Available at 10.1002/j.medmic.2023.100085
75 Folayan A.D., Akintunde,J.K, Akamo A.J.,& Oyelakin, (2023). The Intervention of
oil constituents from Garcinia cola against epidermal growth factor receptor in breast
cancer using In-silico analysis. Informatics in medicine unlocked 40:12185. Published
by Elsevier. Available at 10.1002/j.imedun.2023.12185

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30th Convocation Ceremonies

Award of First Degree to deserving graduands