COURSE CODE: VBB 202
COURSE TITLE: Biochemistry of Proteins & Molecular Biology
NUMBER OF UNITS: 3 Units
COURSE DURATION: Three hours per week
COURSE DETAILS:
Course Coordinator: Dr (Mrs) Funmilola Clara Thomas DVM., M.Sc.
Email: eraforosi@yahoo.com
Office Location: Glass house, COLVET
Other Lecturers: Dr Babatunde Samuel Okediran B.Sc., DVM., M.Sc
Course Synopsis
Protein; classification, structure and functions. Amino acids, Peptides and peptide bonds; essential and non-essential amino acids. Metabolism of amino acids: transamination, oxidativedeamination, decarboxylation etc. urea cycle. Interconversions of threonine. In born errors of metabolism. Chemistry asnd structure of nucleic acids. Cataboliosm of purines, pyrimidines and nucleotides; disorders of purine and pyrimidine metabolism. Plasma proteins, structure and fucntions; blood clotting mechanisms, iron; sources absorbtion, distribution in the body and excretion; anemia; hemochromatosis. Heamoglobin/; structure, propreties and functiioons. Metabolism of porphyrin. Porphyrinurias and jaundice. Heamoglobinopathies. HbS thalassemias, haemophilia etc. Gene cloning and application of recombinant DNA technology in veterinary medicine. Immunoglobulins: typoes structures and functions. Antigens and antigenis determinants. Retroviruss, molecular bases and involvement in cancer; proto-oncogenes and oncogenes. Translocation and gene arrangement in disease state of animals.